A service agreement exists between the NC3Rs and the MRC. Register for our upcoming webinars and watch recordings of past presentations on a wide range of 3Rs topics. Two major alternatives to in vivo animal testing are in vitro cell culture ⦠Demonstrating the 3Rs in principle and practice. Guidance on addressing the 3Rs aspects of a Home Office project licence application. Include all words in search. Opportunities to refine the use of laboratory zebrafish, including common procedures. Resources and information on the 3Rs aimed at a non-specialist audience. Early career researchers (ECRs) Examples of successful grant applications for ECRs will be added shortly. bodies require that their grant holders do this. Je-S is used by AHRC, BBSRC, EPSRC, ESRC, MRC, NERC and STFC (formerly CCLRC and PPARC), as well as the Technology Strategy Board (TSB), Energy Technologies Institute (ETI) and National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), to provide their communities with electronic grant services. Join us on Tuesday 8 June to celebrate this year's 3Rs Prize winner. Resources to help you strengthen the research culture of your group or institution through applying the 3Rs effectively. Read about our programme of events celebrating our open innovation programme's first ten years. Please: read the Aims & Scope to gain an overview and assess if your manuscript is suitable for this journal;; use the Microsoft Word template or LaTeX template to prepare your manuscript;; make sure that issues about publication ethics, research ethics, copyright, authorship, figure formats, data and references format have ⦠To be eligible for a grant of £150,000, you must be undertaking a project that will create at least 27 jobs, and a to secure a grant of £500,000, the project will need to create at least 90 posts. Select the relevant grant type from the list below or the menu on the right. Part 1 â Small acts to make a big impact, ARRIVE guidelines 2.0 now available in six languages. Further information can be found here. Resources and outputs from our programmes related to laboratory rodent welfare. Introducing ARRIVE 2.0. Guidance and resources to help applicants address the 3Rs aspects of a Home Office project licence application. We provide information and guidance on the latest knowledge to improve laboratory animal welfare. In ARRIVE 2.0, we have improved the clarity of the guidelines, prioritised the items, added new information, and generated the accompanying Explanation and Elaboration (E&E) document to provide context and rationale for each item [] (also available at https://www.arriveguidelines.org).New additions comprise inclusion and ⦠Refining blood sampling from laboratory animals - advice on technique, route and volumes. For research projects costing more than £350,000. Instructions for Authors. "Improving biological integration of osseous and dermal tissues in macaque cranial implants" (co-PI) New Investigator Research Grant, MRC. NC3Rs grant holders with more than 12 months remaining on their NC3Rs grant, at the time of application, are not permitted to apply as a Primary Investigator for further NC3Rs funding (excluding CRACK IT, Skills and Knowledge Transfer and Strategic Awards – please contact the Office to discuss). Videos: non-aversive mouse handling in practice. We are offering awards of up to £1,500 to support NC3Rs-funded researchers past and present to engage the public with the approaches being taken to replace, reduce and refine animal use in science. A dedicated website of online tutorials and guidance to support the adoption of best practice for commonly used procedures in animal research. A fundamental goal of the Animal Welfare Act and the accompanying regulations is the minimization of animal pain and distress … Refining the housing and husbandry of common laboratory animal species. Special Project Grants. The examples of successful applications below relate to a variety of response mode/project grant schemes across our portfolio of funders. The funding is available as an open rolling call, where the applications are reviewed quarterly by the NC3Rs Office. The concept was developed by Russell and Burch in a 1959 book entitled Principles of Humane Experimental Technique (link is external). Where a change to Our Terms and Conditions requires a new policy and or These grant conditions, together with the grant award letter and the funding policies, ... the principles in the NC3Rs ... CDD Projects: Where the Grant Activities involve a CDD Project, the Host Institution will enter into a CDD Agreement. Resources to help researchers access and use human tissue. Highlight search results % Search The NC3Rs is an autonomous body responsible for setting and delivering its strategy and managing its resources. Learn more about why the single-use of needles should be standard practice and how to implement this in your facility. We provide a range of funding mechanisms to support projects, infrastructure, and training and career development. Grant types. Shortcuts. Further information can be found at www.nc3rs.org.uk. 94-1J-CX-0055 NC3RS JAN ACQUISITION~ @ Project title: Tire Deflator System for Use at Law Enforcement Checkpoints. Completion date: Project manager:. Where the use of animals is still required, we support researchers to design the best experiments so that their methods and findings are robust and reproducible. The NC3Rsâ ARRIVE guidelines, for example, lay out criteria that should be met in reporting animal studies in order that their results and conclusions can be properly evaluated by readers. ... open access portal for our Grant holders to showcase their 3Rs research. Submission Checklist. Resources to help you improve the design and reporting of your in vivo research. For this purpose, a clinical trial is defined as any research project that assigns human subjects prospectively to intervention or comparison groups to study the cause-and-effect relationship between a medical intervention and a health outcome. Resources to aid researchers improve the design and reporting of research using animals. The grant can go towards costs such as the building of new infrastructure, machinery, equipment, recruitment , staff and modern technology. A new review paper co-authored by NC3Rs staff sets out opportunities to refine vaccine studies that use non-human primates. Posted: 12th March 2018 The National Centre for the 3Rs (NC3Rs) – an organisation dedicated to replacing, refining and reducing the use of animals in research and testing – has awarded its top prize for a research paper by a team from the Department of Computer of … Four new awards will support early career researchers to prepare for an independent career in their chosen 3Rs field. How we support funders to embed the 3Rs in their policies and practice. Read our latest blog post on creating a 3Rs legacy. NIJ Grant award number:. UK Government funding bodies (inclusive of NIHR) NIHR. Upcoming webinars and recordings of past webinars on different 3Rs topics. Part 1 â Small acts to make a big impact, about ARRIVE guidelines 2.0 now available in six languages, Gibbs Building, 215 Euston Road, London, NW1 2BE | Tel: 020 7611 2233 | Fax: 020 7611 2260 | enquiries@nc3rs.org.uk, https://nc3rs.org.uk/events/webinar-nc3rs-3rs-prize-announcement, https://nc3rs.org.uk/news/nc3rs-and-3rs-during-covid-19, https://nc3rs.org.uk/news/10-years-cracking-it, https://www.nc3rs.org.uk/research-culture-and-3rs, https://nc3rs.org.uk/news/legacy-part-1-small-acts-make-big-impact, Refining non-human primate vaccine studies in the age of COVID-19, Whatâs in a legacy? C .,",',* The reference numbers of relevant project and personal licenses should be quoted. Resources on this positive handling technique, provided by the Gaskill Lab at Purdue University. A range of resources to help animal care staff implement the 3Rs. An update on what we are doing to support the research community. The âGrant Typeâ section includes a list of all options appropriate to the MRC âCallâ selected within âProject Detailsâ of the Je-S form. Guidance on key considerations and resources for researchers returning to working with laboratory animals. Posters and other resources on the use of grimace scales to assess pain in laboratory animals. Shortcuts. 3Rs alternatives refer to the reduction, refinement, and replacement of animal use in research, testing, and teaching. Sources of information and advice include the website of the UKâs National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs; www.nc3rs. Grant Guidelines Topics on this page Grants The Parsemus Foundation’s mission is to create meaningful improvements in human and animal health and welfare by advancing innovative and neglected medical research. Alternatives to animal testing are the development and implementation of test methods that avoid the use of live animals.. Find out more: About the 3Rs | About the NC3Rs, Webinar: The NC3Rs 3Rs Prize Announcement. The clinical trial registration number should be included at the end of the abstract of the article. Applicants are required to select one of the available options from the list, which is most relevant to their proposal. Hear from animal care staff championing non-aversive mouse handling in their facilities. Research Grants. Embedding the 3Rs in your return to research plans. To make the most use of limited resources, the Parsemus Foundation works by funding key proof-of-concept studies and then publicizing them so that advances change … Grant … "Contribution of Spinal Commissural Circuits to Bimanual Co-ordination" (PI) Project Grant, NC3Rs. Opportunities to refine the use of non-human primates. We provide an extensive library of 3Rs resources. NC3Rs programmes in drug and chemical safety testing. NC3Rs. Toxicology and regulatory sciences resources. The university's School of Sport, Exercise and Health Sciences will use the funding to learn how to restore skeletal muscle function after significant soft tissue injury. advice addressing the 3Rs in grant and project licence applications, training opportunities, for example on good quality experimental design and reporting, research funding opportunities - from project grants to early career awards. How to strengthen the research culture of your group or institution through applying the 3Rs effectively. Advice and resources for researchers and animal care staff. Guidance on re-establishing colonies following COVID-19 lockdown or any other interruption. We help the research community use the latest science and technology to replace animal studies, providing new approaches for biomedical research and avoiding the time and cost associated with in vivo models. For research projects (basic science and clinical) costing up to £350,000. Online modules funded by the NC3Rs, which are freely available for training and continuing professional development. Register for our upcoming webinars and watch recordings of past presentations on a wide range of 3Rs topics. Please: read the Aims & Scope to gain an overview and assess if your manuscript is suitable for this journal;; use the Microsoft Word template or LaTeX template to prepare your manuscript;; make sure that issues about publication ethics, research ethics, copyright, authorship, figure formats, data and references format have ⦠We lead the discovery and application of new technologies and approaches to replace, reduce and refine the use of animals for scientific purposes. Primarily funded by Government, the NC3Rs is also supported by the charitable and private sectors. Information to help with the implementation of approaches to reduce and refine the use of GA mice. Submission Checklist. The five new members bring expertise in animal welfare, neurobiology, glycobiology, systems biology and in vitro toxicology. Gibbs Building, 215 Euston Road, London, NW1 2BE | Tel: 020 7611 2233 | Fax: 020 7611 2260 | enquiries@nc3rs.org.uk, https://nc3rs.org.uk/news/nc3rs-and-3rs-during-covid-19, https://nc3rs.org.uk/breeding-and-colony-management, https://nc3rs.org.uk/embedding-3rs-covid-19-return-research-plans, https://nc3rs.org.uk/3rs-advice-project-licence-applicants, https://www.nc3rs.org.uk/Toxicology-and-Regulatory-Sciences-resources, https://nc3rs.org.uk/e-learning-resources, https://www.nc3rs.org.uk/non-aversive-mouse-handling-practice, Embedding the 3Rs in COVID-19 return to research plans, 3Rs in toxicology and regulatory sciences, Non-human primate accommodation, care and use, Responsibility in the use of animals in bioscience research. Each award is for £50k, with the Medicines Discovery Catapult providing matched in-kind contributions including access to industrial expertise, facilities and equipment. We particularly encourage applications that integrate a range of disciplines or include an industrial partner. Project Grant, BBSRC. We fund research, support training and development, and stimulate changes in policy, regulations and practice. A total of £2m is available to fund the development of 3Rs approaches and technologies from any area of medical, biological or veterinary research. All grant holders using animals must adhere to the Guidelines for the Welfare and Use of Animals in Cancer Research as set out by Workman and implement the principles in the NC3Rs guidelines (including justification of species, details of power A monthly podcast highlighting the latest 3Rs research, presented by Lab Animal, the North American 3Rs Collaborative and the NC3Rs. Loughborough University has secured a £100,000 grant for a new research project that aims to produce a model for the identification of novel wound therapeutics. Dr Alasdair Nisbet shares how he maximised the long-term impact of his 3Rs research. Grant Terms and Conditions. Animal testing, also known as animal experimentation, animal research and in vivo testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study.This approach can be contrasted with field studies in which animals are observed in their natural environments or habitats. NC3RS" JAN ACQUISiTiONS INTEGRATING STRUCTURED FINES IN FOUR OREGON COUNTIES In The Prepared for Oregon Criminal Justice Council by Jody Forman and David Factor partial fulfillment of the requirements Grant # 91-SD-CX-0003 from the U.S. Department of Justice Bureau of Justice Assistance for February 1995 v .' Learn more about current opportunities to join the NC3Rs team. Guidance and resources to help applicants address the 3Rs aspects of a Home Office project licence application. Examples coming soon . Online modules funded by the NC3Rs, which are freely available for training and continuing professional development. Resources on rat tickling and how it can be used to promote positive human-animal interactions, provided by the Gaskill Lab at Purdue University. Our quarterly newsletter for animal technicians can help you discover new ways to put the 3Rs into practice in your facility. COVID-19 lockdown) with an emphasis on minimising the number of mice used. Read or subscribe to our e-newsletter Tox News and download our bibliography. Links to publications, other online resources, and video and training materials are also provided. Project Grants. The guidelines are now available in French, German, Chinese, Dutch, Portuguese and Italian. For auditing purposes, the Terms and Conditions applicable at the time of the activity or purchase resulting in a subsequent charge to the Training Grant will apply. org.uk: Appendix 1B). Celebrating 10 years of our challenge-led, milestone-driven funding competition, CRACK IT Challenges. This grant type supports funding for basic science research. Read detailed 3Rs method articles from our grant holders via our open access portal. Instructions for Authors. International 3Rs prize goes to human-based computer models which could replace animal testing. Guidance on re-establishing colonies after a pause (e.g. Opportunities to refine the use of laboratory zebrafish, including common procedures. "Bilateral organisation in the spinal cord" (PI) Project grant, BBSRC. A dedicated, open access portal for our Grant holders to showcase their 3Rs research. Discover how Dr Alasdair Nisbet planned his 3Rs legacy and how it has furthered his research.Â. 30 April, 1995 (Demonstration postponed at request of INS) Mr. Bert Soleau Project manager's telephone number: 703-234-9400 The 3Rs developed in the context of laboratory research have been Funding: This work was supported by the National Institutes of Health [grant numbers xxxx, yyyy]; the Bill & Melinda Gates Foundation, Seattle, WA [grant number zzzz]; and the United States Institutes of Peace [grant number aaaa]. It is not an independent public bodyand for this reason it operates under the umbrella of the Medical Research Council (MRC), using some of the MRC administrative systems. The T2T scheme offers NC3Rs-funded researchers the opportunity to develop a collaborative project with Medicines Discovery Catapult, building upon their original NC3Rs grant. Resources to help laboratory animal technicians implement the 3Rs. Resources to help laboratory animal technicians implement the 3Rs, including our quarterly Tech3Rs newsletter. There is widespread agreement that a reduction in the number of animals used and the refinement of testing to reduce suffering should be important goals for the industries involved. 3Rs advice for project licence applicants. Get monthly updates in your inbox from the NC3Rs on funding opportunities, events and publications. This includes guidelines, practical information and themed hubs. Please do get in touch with Ellen (ellen.forty@nc3rs.org.uk) with any 3Rs or NC3Rs queries you might have. The 2020 NC3Rs Project grant call is now open. Key considerations and resources for researchers working with laboratory animals. It is not necessary to include detailed descriptions on the program or type of grants and awards. about Refining non-human primate vaccine studies in the age of COVID-19, about Whatâs in a legacy?
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